The psychedelic escape from depression (2024)

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Clinical trials suggest that psilocybin — the active ingredient in magic mushrooms — can provide durable remission from an increasingly common mental health condition.

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In January 2023, Oregon is due to embark on a groundbreaking real-world experiment in psychedelic medicine. This follows a ballot measure in 2020, in which voters called on the state to begin creating the infrastructure needed to make the hallucinogenic drug psilocybin available as a treatment for mental-health disorders such as depression and anxiety. Canada made a similar move in January 2022, albeit with far more restrictions, allowing designated clinicians to prescribe psilocybin to people with debilitating mental illnesses, such as severe, treatment-resistant depression.

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Nature 609, S87-S89 (2022)

doi: https://doi.org/10.1038/d41586-022-02872-9

This article is part of Nature Outlook: Psychedelic medicine, an editorially independent supplement produced with the financial support of third parties. About this content.

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Related Articles

  • Psychedelic medicine faces the acid test

  • Taking the tripping out of psychedelic medicine

  • Hope that psychedelic drugs can erase trauma

  • How MDMA resensitizes the brain

  • Finding medical value in mescaline

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Subjects

  • Drug discovery
  • Depression
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  • Psychology

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